Yes, That’s doable.

You just need to change the database configuration array passed to the constructor of jqgrid(…);

e.g.

$g1 = new jqgrid($db1);
$g2 = new jqgrid($db2);

Where $db1 and $db2 is the configuration array like:

$db1 = array();
$db1["type"] = "mysqli";
$db1["server"] = "127.0.0.1";
$db1["user"] = "user"; // username
$db1["password"] = "pass"; // password
$db1["database"] = "griddemo1"; // database